Taking mangosteen alongside medications that slow down blood clotting could increase the risk of bruising and bleeding. Mangosteen extracts and xanthones have been reported to eliminate 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,20-azino-bis- (3-ethylbenziazoline-6-sulphonic) (ABTS) and peroxynitrite radicals (Yoshikawa et al.). A patented mangosteen juice and extract, aloe vera gel and decaffeinated green tea made up 10% of the wet weight of the beverage. The reason for using 60 participants is to reduce individual variability during ingestion of the mangosteen product, since a large discrepancy was observed in the absorption rate of xanthone in mangosteen juice (Chitchumroonchokchai et al.).It is always important to consult a qualified doctor for advice and to inform them about ongoing treatments and conditions before consuming mangosteen, due to its potential benefits.
All parts of the mangosteen plant, such as the leaves, roots, bark, whole fruit, stem, arils (an additional layer of seeds, usually colored and hairy or fleshy), seeds and heartwood, are consumed in different forms as they contain rich bioactive compounds that can have numerous health benefits. It has been suggested that mangosteen might have benefits for the immune response and possible anti-cancer activities due to the pericarp of the fruit.